Article
Opposite phenotypes of cancer and aging arise from alternative regulation of common signaling pathways.
Annals of the New York Academy of Sciences - 1 Dec 2003
Ukraintseva Svetlana V, Yashin Anatoly I
Abstract excerpt
Phenotypic features of malignant and senescent cells are in many instances opposite. Cancer cells do not "age"; their metabolic, proliferative, and growth characteristics are opposite to those observed with cellular aging (both replicative and functional). In many such characteristics cancer cell...
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