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Article

Retinoic acid-induced CD38 antigen as a target for immunotoxin-mediated killing of leukemia cells.

Molecular cancer therapeutics - 1 Mar 2004

Mehta Kapil, Ocanas Larry, Malavasi Fabio, Marks John W, Rosenblum Michael G

Abstract excerpt

A major obstacle in the successful delivery of antibody-based therapeutics to tumor cells is the heterogeneity of target antigen expression. We reported previously that retinoic acid (RA) is a potent and selective inducer of the cell-surface antigen CD38 in myeloid leukemia cells. The purpose of this study was to determine whether the RA-induced CD38 antigen could be a target for an anti-CD38-based immunotoxin to...

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PMID: 15026555

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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