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Article

Integrating drug pharmacokinetics for phenotyping individual renin response to angiotensin II blockade in humans.

Hypertension (Dallas, Tex. : 1979) - 1 Apr 2004

Azizi Michel, Bissery Alvine, Lamarre-Cliche Maxime, Ménard Joël

Abstract excerpt

Renin release into plasma has been used to investigate the drug dose-dependence of renin-angiotensin system inhibition because it is proportional to the interruption of the permanent negative feedback loop of angiotensin II on renin secretion. We investigated the 24-hour between-subject differenc...

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Identifiers

PMID: 15023936
DOI: 10.1161/01.HYP.0000125698.00128.64

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15023936-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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