Nonmuscle myosin heavy-chain gene MYH14 is expressed in cochlea and mutated in patients affected by autosomal dominant hearing impairment (DFNA4).

doi:10.1086/383285

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Article

Nonmuscle myosin heavy-chain gene MYH14 is expressed in cochlea and mutated in patients affected by autosomal dominant hearing impairment (DFNA4).

American journal of human genetics - 1 Apr 2004

Donaudy Francesca, Snoeckx Rik, Pfister Markus, Zenner Hans-Peter, Blin Nikolaus, Di Stazio Mariateresa, Ferrara Antonella, Lanzara Carmen, Ficarella Romina, Declau Frank, Pusch Carsten M, Nürnberg Peter, Melchionda Salvatore, Zelante Leopoldo, Ballana Ester, Estivill Xavier, Van Camp Guy, Gasparini Paolo, Savoia Anna

Abstract excerpt

Myosins have been implicated in various motile processes, including organelle translocation, ion-channel gating, and cytoskeleton reorganization. Different members of the myosin superfamily are responsible for syndromic and nonsyndromic hearing impairment in both humans and mice. MYH14 encodes one of the heavy chains of the class II nonmuscle myosins, and it is localized within the autosomal dominant hearing...

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Identifiers

PMID: 15015131
DOI: 10.1086/383285
PMCID: PMC1181955

Genes

MYH14

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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