Article
Fine mapping of the chromosome 2p12-16 dyslexia susceptibility locus: quantitative association analysis and positional candidate genes SEMA4F and OTX1.
Psychiatric genetics - 1 Mar 2002
Francks Clyde, Fisher Simon E, Olson Richard K, Pennington Bruce F, Smith Shelley D, DeFries John C, Monaco Anthony P
Abstract excerpt
A locus on chromosome 2p12-16 has been implicated in dyslexia susceptibility by two independent linkage studies, including our own study of 119 nuclear twin-based families, each with at least one reading-disabled child. Nonetheless, no variant of any gene has been reported to show association with dyslexia, and no consistent clinical evidence exists to identify candidate genes with any strong a priori logic. We...
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