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Article

A locus on 2p12 containing the co-regulated MRPL19 and C2ORF3 genes is associated to dyslexia.

Human molecular genetics - 15 Mar 2007

Anthoni Heidi, Zucchelli Marco, Matsson Hans, Müller-Myhsok Bertram, Fransson Ingegerd, Schumacher Johannes, Massinen Satu, Onkamo Päivi, Warnke Andreas, Griesemann Heide, Hoffmann Per, Nopola-Hemmi Jaana, Lyytinen Heikki, Schulte-Körne Gerd, Kere Juha, Nöthen Markus M, Peyrard-Janvid Myriam

Abstract excerpt

DYX3, a locus for dyslexia, resides on chromosome 2p11-p15. We have refined its location on 2p12 to a 157 kb region in two rounds of linkage disequilibrium (LD) mapping in a set of Finnish families. The observed association was replicated in an independent set of 251 German families. Two overlapping risk haplotypes spanning 16 kb were identified in both sample sets separately as well as in a joint analysis. In...

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Source

Identifiers

PMID: 17309879
DOI: 10.1093/hmg/ddm009

Genes

MRPL19
DCDC2
ROBO1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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