Article
Involvement of IL-9 in the bronchial phenotype of patients with nasal polyposis.
The Journal of allergy and clinical immunology - 1 Mar 2004
Tsicopoulos Anne, Shimbara Ayako, de Nadai Patricia, Aldewachi Oday, Lamblin Catherine, Lassalle Philippe, Walls Andrew F, Sénéchal Stéphanie, Levitt Roy C, Darras Jean, Hamid Qutayba, Wallaert Benoît
Abstract excerpt
BACKGROUND: Nasal polyposis (NP) is frequently associated with asthma. In this disease, asymptomatic bronchial hyperresponsiveness (BHR) is thought to precede the development of asthma. IL-9 and its receptor have been reported as candidate genes for asthma and to be associated with BHR. OBJECTIVE: The objective of this study was to assess the contribution of 11-9 to the pathogenesis of BHR in NP by comparing the...
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