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Article

Role of caspases in male infertility

1 Jan 2004

Abstract excerpt

Apoptosis is characterized by a variety of changes resulting in the recognition and phagocytosis of apoptotic cells. Caspases (cysteinyl aspartate-specific proteinases) play a central role in the regulation of apoptosis in the human seminiferous epithelium. They are expressed as inactive proenzymes and participate in a cascade triggered in response to pro-apoptotic signals. To date, 14 caspases have been...

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PMID: 15005463
DOI: 10.1093/humupd/dmh003

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