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Lethal and Non-Lethal Functions of Caspases in the DNA Damage Response

10 Jun 2022

Abstract excerpt

Members of the caspase family are well known for their roles in the initiation and execution of cell death. Due to their function in the removal of damaged cells that could otherwise become malignant, caspases are important players in the DNA damage response (DDR), a network of pathways that prevent genomic instability. However, emerging evidence of caspases positively or negatively impacting the accumulation of...

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PMID: 35741016
DOI: 10.3390/cells11121887

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