Article
Presence and significance of somatic cell apoptosis markers in human ejaculated spermatozoa.
Reproductive biomedicine online - 1 Jan 2000
Oehninger Sergio, Morshedi Mahmood, Weng S-L, Taylor Steve, Duran Hakan, Beebe Stephen
Abstract excerpt
Ejaculated spermatozoa, particularly in infertile men, have been shown to display morphological and biochemical features that are typical of an apoptotic phenotype in somatic cells. Deregulation of apoptosis is known to play roles in a number of disease processes, but roles for apoptosis in ejaculated spermatozoa and male infertility are poorly defined or have not been studied. Preliminary data demonstrated that...
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