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Article

Mutation analysis of the KAL gene in female patients with gonadotropin-releasing hormone deficiency.

Yonsei medical journal - 29 Feb 2004

Lee Sook-Hwan, Han Jung-Hee, Cho Sung-Won, Lee Whee-Hyun, Cha Kwang-Yul, Lee Mee-Hwa

Abstract excerpt

Isolated gonadotropin-releasing hormone (GnRH) deficiency, including Kallmann's syndrome (KS) and idiopathic hypogonadotropic hypogonadism (IHH), is a congenital disorder, which is characterized by a functional deficit in hypothalamic GnRH secretion. Despite recent advances in the understanding of the pathogenesis of the X-linked form of KS as the identification of the KAL gene (Xp22.3), the genetic basis of the...

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Source

Identifiers

PMID: 15004876
DOI: 10.3349/ymj.2004.45.1.107

Genes

IHH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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