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Article

KAL1 mutations are not a common cause of idiopathic hypogonadotrophic hypogonadism in humans.

Molecular human reproduction - 1 Mar 2007

Bhagavath Balasubramanian, Xu Ning, Ozata Metin, Rosenfield Robert L, Bick David P, Sherins Richard J, Layman Lawrence C

Abstract excerpt

Hypogonadotrophic hypogonadism results in the absence of puberty and if left untreated leads to infertility. Mutations in KAL1 are known to account for some of the cases of Kallmann syndrome. The aim of this study was to determine the prevalence of KAL1 mutations in a large number of patients with idiopathic hypogonadotrophic hypogonadism (IHH). One hundred and thirty eight patients (109 males and 29 females)...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17213338
DOI: 10.1093/molehr/gal108

Genes

IHH

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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KAL1 mutations are not a common cause of idiopathic hypogonadotrophic hypogonadism in humans.PMID 17213338Read ↗

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