Article
Measurement of anti-D intrinsic affinity with unlabeled antibodies.
Transfusion - 1 Mar 2004
Debbia Martine, Lambin Patrick
Abstract excerpt
BACKGROUND: The method most commonly used for measuring the affinity of MoAbs specific for the D antigen is a binding assay using 125I-labeled MoAb. Although the method is relatively simple, there are several drawbacks that can lead to inaccurate results. The objective of the present work was to develop a method for the determination of the affinity of anti-D MoAb using unlabelled antibodies. STUDY DESIGN AND...
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