Article
NKp46 defines a subset of bovine leukocytes with natural killer cell characteristics.
European journal of immunology - 1 Mar 2004
Storset Anne K, Kulberg Siri, Berg Ingvild, Boysen Preben, Hope Jayne C, Dissen Erik
Abstract excerpt
Natural killer (NK) cells have not previously been precisely identified or characterized in cattle or any other ruminant species. We have generated a monoclonal antibody against bovine NKp46, which is expressed exclusively by NK cells in man. NKp46+ cells comprised 1-10% of blood mononuclear cells in cattle, and did not stain with antibodies against CD3, CD4, TCR1, B cell or granulocyte markers. The majority of...
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