Article
Colchicine nonresponsiveness in familial Mediterranean fever: clinical, genetic, pharmacokinetic, and socioeconomic characterization.
Seminars in arthritis and rheumatism - 1 Feb 2004
Lidar Merav, Scherrmann Jean-Michel, Shinar Yael, Chetrit Angela, Niel Elisabeth, Gershoni-Baruch Ruth, Langevitz Pnina, Livneh Avi
Abstract excerpt
OBJECTIVES: To identify the ethnic, clinical, genetic, and pharmacokinetic correlates of colchicine treatment failure in patients with familial Mediterranean fever (FMF). METHODS: Fifty-nine FMF patients, unresponsive to a daily dose of > or =2 mg colchicine, were compared with 51 colchicine-resp...
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