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Article

Unresponsiveness to colchicine therapy in patients with familial Mediterranean fever homozygous for the M694V mutation.

The Journal of rheumatology - 1 Jan 2010

Soylemezoglu Oguz, Arga Mustafa, Fidan Kibriya, Gonen Sevim, Emeksiz Hamdi Cihan, Hasanoglu Enver, Buyan Necla

Abstract excerpt

OBJECTIVE: More than 50 disease-associated mutations of the Mediterranean fever gene (MEFV) have been identified in familial Mediterranean fever (FMF), some of which were shown to have different clinical, diagnostic, prognostic, and therapeutic implications. The aim of our study was to define the frequency of mutation type, genotype-phenotype correlation, and response to colchicine treatment in patients with FMF....

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Child
Child, Preschool
Colchicine
Familial Mediterranean Fever
Genetic Association Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genetic Predisposition to Disease

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Identifiers

PMID: 20008920
DOI: 10.3899/jrheum.090273

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MEFV

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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Unresponsiveness to colchicine therapy in patients with familial Mediterranean fever homozygous for the M694V mutation.PMID 20008920Read ↗

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Genotype-phenotype correlation in children with familial Mediterranean fever in a Turkish population.Semantic proximity Read ↗

Genotype Mutations in Egyptian Children with Familial Mediterranean Fever: Clinical Profile, and Response to ColchicineSemantic proximity Read ↗

Familial Mediterranean fever (FMF) phenotype in patients homozygous to the MEFV M694V mutation.Semantic proximity Read ↗

The clinical and genetical features of 124 children with Familial Mediterranean fever: experience of a single tertiary center.Semantic proximity Read ↗

Familial Mediterranean fever in childhood: a single-center experience.Semantic proximity Read ↗

Prophylactic colchicine for familial Mediterranean fever: response rates revisited.Semantic proximity Read ↗

Genotype-phenotype associations in familial Mediterranean fever: a study of 500 Egyptian pediatric patients.Semantic proximity Read ↗

Relationship between clinical findings and genetic mutations in patients with familial Mediterranean fever.Semantic proximity Read ↗

Familial mediterranean fever: a fascinating model of inherited autoinflammatory disorder.Semantic proximity Read ↗

Mutations in the MEFV gene in a large series of patients with a clinical diagnosis of familial Mediterranean fever.Semantic proximity Read ↗

Comorbidities and phenotype-genotype correlation in children with familial Mediterranean fever.Semantic proximity Read ↗

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