Article
Susceptibility to tuberculosis: clues from studies with inbred and outbred New Zealand White rabbits.
Infection and immunity - 1 Mar 2004
Dorman Susan E, Hatem Christine L, Tyagi Sandeep, Aird Katherine, Lopez-Molina Javier, Pitt M Louise M, Zook Bernard C, Dannenberg Arthur M, Bishai William R, Manabe Yukari C
Abstract excerpt
The rabbit model of tuberculosis (TB) is important because rabbits develop a disease that is similar to TB in humans, namely, granulomas with caseous necrosis, liquefaction, and cavities. We describe here a comparison of inbred and outbred New Zealand White rabbits infected by aerosol with either Mycobacterium tuberculosis Erdman or H37Rv strain. Five weeks after infection with either bacillary strain, the inbred...
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