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Article

Gap statistics for whole genome shotgun DNA sequencing projects.

Bioinformatics (Oxford, England) - 10 Jul 2004

Wendl Michael C, Yang Shiaw-Pyng

Abstract excerpt

MOTIVATION: Investigators utilize gap estimates for DNA sequencing projects. Standard theories assume sequences are independently and identically distributed, leading to appreciable under-prediction of gaps. RESULTS: Using a statistical scaling factor and data from 20 representative whole genome shotgun projects, we construct regression equations that relate coverage to a normalized gap measure. Prokaryotic...

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PMID: 14962917
DOI: 10.1093/bioinformatics/bth120

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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