Article
Behavioral alterations induced by repeated testing in C57BL/6J and 129S2/Sv mice: implications for phenotyping screens.
Genes, brain, and behavior - 1 Feb 2004
Võikar V, Vasar E, Rauvala H
Abstract excerpt
The C57BL/6JOlaHsd and 129S2/SvHsd mice were tested in a battery designed for behavioral phenotyping of genetically modified mice. The study was performed in order to reveal the effect of training history on the behavior by comparison with the experimentally naive mice in the same tests. Significant strain differences were obtained in all experiments. Previous handling and testing reduced exploratory activity and...
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