Article
Molecular basis and allele specific screening of apolipoprotein CIISt. Michael.
Clinical biochemistry - 1 Oct 1992
Hegele R A, Tu L, Maguire G F, Connelly P W
Abstract excerpt
The DNA basis for a circulating nonfunctional variant apoCII, designated apoCIISt. Michael (CII-S) is a shifted reading frame. We developed two amplification primers to screen for CII-S. One contained wild type apoCII sequence and the other contained the sequence for CII-S. Allele-specific polymerase chain reaction (ASPCR) of the apoCII gene from the CII-S proband and her relatives showed unambiguous...
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