Article
Genetic analysis using the polymerase chain reaction.
Annual review of genetics - 1 Jan 1992
Erlich H A, Arnheim N
Abstract excerpt
The ability of PCR to amplify a specific DNA segment from a complex template in an automated reaction has made molecular analysis more accessible both to basic research and diagnostic laboratories. Modifications of the basic PCR method using generic primers now allow DNA amplification even in the absence of specific nucleotide sequence information. Although PCR has proved extremely valuable for detecting the...
Topics
- Biological Evolution
- Chromosome Mapping
- DNA
- Female
- Genetic Diseases, Inborn
- Genetic Linkage
- Genetic Techniques
- Genetic Variation
- Genotype
- Humans
- Male
- Polymerase Chain Reaction
