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Article

Survival motor neuron (SMN) protein interacts with transcription corepressor mSin3A.

The Journal of biological chemistry - 9 Apr 2004

Zou Junhui, Barahmand-pour Fariba, Blackburn Michael L, Matsui Yoshito, Chansky Howard A, Yang Liu

Abstract excerpt

Spinal muscular atrophy (SMA) is the leading genetic cause of infant mortality. SMA results from loss of survival motor neuron (SMN) expression and subsequent death of motor neuron cells. To study SMN-associated proteins that may be involved in transcriptional regulation, we carried out immunopre...

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Identifiers

PMID: 14749338
DOI: 10.1074/jbc.M309218200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14749338-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

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Research trail→

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Survival motor neuron (SMN) protein interacts with transcription corepressor mSin3A.PMID 14749338Read ↗

Identification of survival motor neuron as a transcriptional activator-binding proteinSemantic proximity Read ↗

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Gemin5 Binds to the Survival Motor Neuron mRNA to Regulate SMN ExpressionSemantic proximity Read ↗

SMN mutants of spinal muscular atrophy patients are defective in binding to snRNP proteins.Semantic proximity Read ↗

Targeting SR Proteins Improves SMN Expression in Spinal Muscular Atrophy CellsSemantic proximity Read ↗

The SMN Complex at the Crossroad between RNA Metabolism and NeurodegenerationSemantic proximity Read ↗

Gemins modulate the expression and activity of the SMN complexSemantic proximity Read ↗

Genetic circuitry of Survival motor neuron, the gene underlying spinal muscular atrophy.Semantic proximity Read ↗

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A Comprehensive Interaction Map of the Human Survival of Motor Neuron (SMN) ComplexSemantic proximity Read ↗

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