Article
Mutations arising in the wave front of an expanding population.
Proceedings of the National Academy of Sciences of the United States of America - 27 Jan 2004
Edmonds Christopher A, Lillie Anita S, Cavalli-Sforza L Luca
Abstract excerpt
The ability to infer the time and place of origin of a mutation can be very useful when reconstructing the evolutionary histories of populations and species. We use forward computer simulations of population growth, migration, and mutation in an analysis of an expanding population with a wave front that advances at a constant slow rate. A pronounced founder effect can be observed among mutations arising in this...
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