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Article

Multiminicore disease in a family susceptible to malignant hyperthermia: histology, in vitro contracture tests, and genetic characterization.

Archives of neurology - 1 Jan 2004

Guis Sandrine, Figarella-Branger Dominique, Monnier Nicole, Bendahan David, Kozak-Ribbens Geneviève, Mattei Jean-Pierre, Lunardi Joël, Cozzone Patrick J, Pellissier Jean-François

Abstract excerpt

BACKGROUND: Histological anomalies associated with malignant hyperthermia (MH) have been scarcely reported. In some patients susceptible to MH (MHS), central cores have been identified and a genetic association has been proposed, but multiminicore lesions have not been systematically reported. OBJECTIVE: To analyze the association between multiminicores and MHS in a large family with MH with an approach combining...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 14732627
DOI: 10.1001/archneur.61.1.106

Genes

RYR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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