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Article

Chronic myopathy in a patient suspected of carrying two malignant hyperthermia susceptibility (MHS) mutations.

Neuromuscular disorders : NMD - 1 Jan 1992

Deufel T, Müller-Felber W, Pongratz D E, Hübner G, Johnson K, Iaizzo P A, Lehmann-Horn F

Abstract excerpt

Malignant hyperthermia (MH) is a pharmacogenetic myopathy triggered by a variety of anaesthetic agents and muscle relaxants. In humans, susceptibility to MH is inherited as an autosomal dominant trait, and susceptible patients do not show a clinically relevant myopathy unless having suffered from a MH crisis. Homozygosity for the MHS trait is thought to be an uncommon finding, and so far only a few cases of...

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Identifiers

PMID: 1300187
DOI: 10.1016/s0960-8966(06)80010-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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