Article
Quantitative Proteomic Analysis of Proteins Released by Neoplastic Prostate Epithelium
1 Jan 2004
Abstract excerpt
Prostate cancer is unusual among neoplasms in that it may be diagnosed at a curable stage through detection of a protein in serum, the serine protease prostate-specific antigen (PSA). PSA is secreted by both normal and neoplastic prostate epithelial cells in response to androgenic hormones and has found widespread use in cancer screening. Because PSA screening is controversial due to sensitivity and specificity...
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