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Article

Demographic heterogeneity explains age-specific patterns of genetic variance in mortality rates.

Experimental gerontology - 1 Jan 2004

Service Philip M

Abstract excerpt

The genetic variance of mortality rates in Drosophila melanogaster increases with age early in life, but declines at intermediate ages. A simulation study was done in order to evaluate two competing explanations for this age-specific pattern: (1) demographic heterogeneity, and (2) binomial sampling effects. The pattern can be explained by demographic heterogeneity among and within genotypes. In contrast, binomial...

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PMID: 14724061
DOI: 10.1016/j.exger.2003.09.014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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