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Article

Demography of genotypes: failure of the limited life-span paradigm in Drosophila melanogaster.

Science (New York, N.Y.) - 16 Oct 1992

Curtsinger J W, Fukui H H, Townsend D R, Vaupel J W

Abstract excerpt

Experimental systems that are amenable to genetic manipulation can be used to address fundamental questions about genetic and nongenetic determinants of longevity. Analysis of large cohorts of ten genotypes of Drosophila melanogaster raised under conditions that favored extended survival has revealed variation between genotypes in both the slope and location of age-specific mortality curves. More detailed...

Topics

Aging
Animals
Drosophila melanogaster
Genotype
Life Expectancy
Mortality

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 1411541
DOI: 10.1126/science.1411541

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1411541-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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