Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hemophilia B Leyden: characteristics and natural history in the International Pediatric Network of Hemophilia Management Registry.

Journal of thrombosis and haemostasis : JTH - 1 Mar 2025

Kartal-Kaess Mutlu, Pinto Fernando, Labarque Veerle, de Kovel Marloes, Nolan Beatrice, Carcao Manuel, d'Oiron Roseline, Mikkelsen Torben Stamm, Ljung Rolf, Andersson Nadine G

Abstract excerpt

BACKGROUND: A unique form of hemophilia B (HB) is HB Leyden. We evaluated the international Pediatric Network on Hemophilia Management Registry (PedNet) database to explore the natural history of HB Leyden, investigate genotype-phenotype associations, and guide clinical decision-making. OBJECTIVES: To assess the association between genetic variants, endogenous factor (F)IX levels over time, treatment, and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age Factors
Share to Clinical Decision-Making

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Factor IX

Share to Genetic Association Studies

Share to Hemophilia B

Share to Hemorrhage

Share to Registries

Share to Time Factors

Source

Identifiers

PMID: 39742973
DOI: 10.1016/j.jtha.2024.12.020

Genes

F9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hemophilia B Leyden: characteristics and natural history in the International Pediatric Network of Hemophilia Management Registry.PMID 39742973Read ↗

Bleeding phenotype according to factor level in 825 children with nonsevere hemophilia: data from the PedNet cohort.Semantic proximity Read ↗

First case report of hemophilia B Leyden in Japan.Semantic proximity Read ↗

Hemophilia B: molecular pathogenesis and mutation analysis.Semantic proximity Read ↗

Inhibitor incidence in an unselected cohort of previously untreated patients with severe haemophilia B: a PedNet studySemantic proximity Read ↗

Genotype-phenotype analyses of Iranian patients with and without hemophilia B Leyden: A single-center studySemantic proximity Read ↗

Prospective observational cohort studies for studying rare diseases: the European PedNet Haemophilia Registry.Semantic proximity Read ↗

Hemophilia A and B: molecular and clinical similarities and differencesSemantic proximity Read ↗

Genotype-phenotype analyses of Iranian patients with hemophilia B (Leyden -) and hemophilia B (Leyden +): A single-center study.Semantic proximity Read ↗

The <scp>CDC</scp> Hemophilia B mutation project mutation list: a new online resourceSemantic proximity Read ↗

Results of genetic analysis of 11 341 participants enrolled in the My Life, Our Future hemophilia genotyping initiative in the United States.Semantic proximity Read ↗

A close insight to factor VIII inhibitor in the congenital hemophilia A.Semantic proximity Read ↗

Impact of SERPINC1 mutation on thrombotic phenotype in children with congenital antithrombin deficiency-first analysis of the International Society on Thrombosis and Haemostasis pediatric antithrombin deficiency database and biorepository.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.