Article
Expression of the SRY-related HMG box protein SOX2 in human gastric carcinoma.
International journal of oncology - 1 Feb 2004
Li Xue-Ling, Eishi Yoshinobu, Bai Yun-Qing, Sakai Hidekazu, Akiyama Yoshimitsu, Tani Masao, Takizawa Touichirou, Koike Morio, Yuasa Yasuhito
Abstract excerpt
SOX2, a SRY-related HMG box protein, is thought to be an important transcription factor during organogenesis, including the stomach although the expression and function are unclear. We investigated SOX2 protein expression to clarify its roles in differentiation and carcinogenesis of the stomach. Using polyclonal SOX2 antibodies, expression of SOX2 in gastric normal mucosae, intestinal metaplasia and carcinomas...
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