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Article

Developing a convenient large animal model for gene transfer to salivary glands <i>in vivo</i>

1 Jan 2004

Abstract excerpt

BACKGROUND: Localized gene transfer to salivary glands has great potential for the treatment of salivary gland, systemic, and oral diseases. The minipig parotid gland, given its volume and morphological similarities to the human parotid gland, may be useful as a large animal model for pre-clinical gene transfer experiments. The purpose of this study was to perform an initial assessment of the efficacy and safety...

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PMID: 14716677
DOI: 10.1002/jgm.476

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