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Article

Evaluation of the Gamma-H2AX Assay for Radiation Biodosimetry in a Swine Model

8 Jul 2013

Abstract excerpt

There is a paucity of large animal models to study both the extent and the health risk of ionizing radiation exposure in humans. One promising candidate for such a model is the minipig. Here, we evaluate the minipig for its potential in γ-H2AX-based biodosimetry after exposure to ionizing radiation using both Cs137 and Co60 sources. γ-H2AX foci were enumerated in blood lymphocytes and normal fibroblasts of human...

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PMID: 23880859
DOI: 10.3390/ijms140714119

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