Article
No pathogenic mutations in the uroplakin III gene of 25 patients with primary vesicoureteral reflux.
The Journal of urology - 1 Feb 2004
Giltay Jacques C, van de Meerakker Judith, van Amstel Hans-Krisian Ploos, de Jong Tom P V M
Abstract excerpt
PURPOSE: The uroplakin III (UPIII) knockout mouse provides a good model for human primary vesicoureteral reflux (VUR). Since to our knowledge no causative genes in human VUR have been identified to date, we wondered whether the UPIII gene might be involved in human primary VUR. Therefore, the UPIII gene was sequenced to see if any mutations could be detected in patients with primary VUR. MATERIALS AND METHODS:...
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