Orphan nuclear receptors, molecular clockwork, and the entrainment of peripheral oscillators.

Abstract excerpt

Here we summarize our work on two aspects of circadian timing: the roles of orphan nuclear receptors in the molecular clockwork, and phase entrainment of peripheral oscillators. With reference to the former, studies on cis-acting regulatory elements within the Bmal1 promoter revealed that REV-ERBalpha, an orphan nuclear receptor provides a link between the positive and negative limbs of the molecular oscillator....

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to ARNTL Transcription Factors
• Share to Body Temperature