Article
Field studies of aflatoxin exposure, metabolism and induction of genetic alterations in relation to HBV infection and hepatocellular carcinoma in The Gambia and Thailand.
Toxicology letters - 1 Dec 1992
Wild C P, Shrestha S M, Anwar W A, Montesano R
Abstract excerpt
The relative contribution of aflatoxins (AF) and hepatitis B virus (HBV) to the aetiology of liver cancer remains to be determined, as does the mechanism of any interaction between these two factors. Methods to measure individual exposure to AF permit the assessment of this possible interaction in field studies. The measurement of AF covalently bound to albumin in peripheral blood has been particularly useful in...
Topics
- Aflatoxins
- Child
- Child, Preschool
- Gambia
- Genes, p53
- Hepatitis B
- Humans
- Liver Neoplasms
- Mutation
- Thailand