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Article

Binding of copper(I) by the Wilson disease protein and its copper chaperone.

The Journal of biological chemistry - 26 Mar 2004

Wernimont Amy K, Yatsunyk Liliya A, Rosenzweig Amy C

Abstract excerpt

The Wilson disease protein (WND) is a transport ATPase involved in copper delivery to the secretory pathway. Mutations in WND and its homolog, the Menkes protein, lead to genetic disorders of copper metabolism. The WND and Menkes proteins are distinguished from other P-type ATPases by the presence of six soluble N-terminal metal-binding domains containing a conserved CXXC metal-binding motif. The exact roles of...

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Identifiers

PMID: 14709553
DOI: 10.1074/jbc.M311213200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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