Article
Association of gene polymorphisms with coronary artery disease in individuals with or without nonfamilial hypercholesterolemia.
Atherosclerosis - 1 Jan 2004
Shimokata Keiko, Yamada Yoshiji, Kondo Takahisa, Ichihara Sahoko, Izawa Hideo, Nagata Kohzo, Murohara Toyoaki, Ohno Miyoshi, Yokota Mitsuhiro
Abstract excerpt
A substantial proportion of individuals with coronary artery disease (CAD) has concomitant hypercholesterolemia. A large-scale association study was performed to identify separately genes that confer susceptibility to CAD in the absence or presence of nonfamilial hypercholesterolemia. The study population comprised 5248 unrelated Japanese individuals, including 3085 subjects with CAD (2350 men, 735 women) and...
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