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Article

Genetic polymorphims in promoter region of osteopontin gene may be a marker reflecting hepatitis activity in chronic hepatitis C patients.

Biochemical and biophysical research communications - 23 Jan 2004

Mochida Satoshi, Hashimoto Michie, Matsui Atsushi, Naito Masashi, Inao Mie, Nagoshi Sumiko, Nagano Makoto, Egashira Tohru, Mishiro Shunji, Fujiwara Kenji

Abstract excerpt

BACKGROUND AND AIMS: Osteopontin, an extracellular matrix protein with RGD motif, is shown to be a cytokine essential for Th1 immune response initiation. Genetic polymorphisms in the osteopontin gene (OPN) determine the magnitude of immunity against rickettsial infection in mice. Similar polymorp...

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Source

Identifiers

PMID: 14706653
DOI: 10.1016/j.bbrc.2003.12.045

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-14706653-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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