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Article

Destabilizing interactions among [PSI(+)] and [PIN(+)] yeast prion variants.

Genetics - 1 Dec 2003

Bradley Michael E, Liebman Susan W

Abstract excerpt

The yeast Sup35 and Rnq1 proteins can exist in either the noninfectious soluble forms, [psi-] or [pin-], respectively, or the multiple infectious amyloid-like forms called [PSI+] or [PIN+] prion variants (or prion strains). It was previously shown that [PSI+] and [PIN+] prions enhance one another's de novo appearance. Here we show that specific prion variants of [PSI+] and [PIN+] disrupt each other's stable...

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Identifiers

PMID: 14704158
DOI: 10.1093/genetics/165.4.1675
PMCID: PMC1462903

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Destabilizing interactions among [PSI(+)] and [PIN(+)] yeast prion variants.PMID 14704158Read ↗

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