Article
[Hepatitis C virus variability and interferon-mediated pathway inhibition].
Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia - 1 Sept 2003
Fernández B, Basaras M, Blanco S, Sánchez S, Arrese E, de las Heras B, Cisterna R
Abstract excerpt
The most important aim of this study was to describe the hypothetical relationship between the PePHD region variability (related to the synthesis of a cellular enzyme pseudosubstrate) of the hepatitis C virus and the response of patients to interferon therapy. This interaction could be a determining factor in the antiviral effect of interferon. All samples (from 24 patients with chronic hepatitis C infection)...
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