Article
Structural characterization and promoter analysis of human potassium channel Kv8.1 (KCNV1) gene.
Gene - 21 Jan 2004
Ebihara Mitsuru, Ohba Hisako, Kikuchi Mika, Yoshikawa Takeo
Abstract excerpt
The voltage-gated K(+) channel (Kv) family comprises four subfamilies: Kv1, Kv2, Kv3 and Kv4. Kv6, Kv7, Kv8 and Kv9 subfamilies have also recently been reported. The gene for Kv8.1 (KCNV1) maps onto chromosome 8q23.3, a locus for benign adult familial myoclonic epilepsy. Despite sequence identity with other K(+) channel genes, KCNV1 does not display K(+) channel activity when expressed in Xenopus oocytes, instead...
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