Article
Pleiotropic phenotypes of fission yeast defective in ubiquinone-10 production. A study from the abc1Sp (coq8Sp) mutant.
BioFactors (Oxford, England) - 1 Jan 2003
Saiki Ryoichi, Ogiyama Yuki, Kainou Tomohiro, Nishi Tomoko, Matsuda Hideyuki, Kawamukai Makoto
Abstract excerpt
We previously constructed two Schizosaccahromyces pombe ubiquinone-10 (or Coenzyme Q10) less mutants, which are either defective for decaprenyl diphosphate synthase or p-hydroxybenzoate polyprenyl diphosphate transferase. To further confirm the roles of ubiquinone in S. pombe, we examined the phenotype of the abc1Sp (coq8Sp) mutant, which is highly speculated to be defective in ubiquinone biosynthesis. We show...
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