Article
Role of the ectodomain of the gp41 transmembrane envelope protein of human immunodeficiency virus type 1 in late steps of the membrane fusion process.
Journal of virology - 1 Jan 2004
Bär Séverine, Alizon Marc
Abstract excerpt
The membrane fusion process mediated by the gp41 transmembrane envelope glycoprotein of the human immunodeficiency virus type 1 (HIV-1) was addressed by a flow cytometry assay detecting exchanges of fluorescent membrane probes (DiI and DiO) between cells expressing the HIV-1 envelope proteins (Env) and target cells. Double-fluorescent cells were detected when target cells expressed the type of chemokine receptor,...
Topics
- Amino Acid Sequence
- Anti-HIV Agents
- Cell Line
- Cell Membrane
- Enfuvirtide
- Flow Cytometry
- Giant Cells
- HIV Envelope Protein gp41
- HIV-1
- HeLa Cells
- Humans
- Membrane Fusion
- Membrane Lipids
- Microscopy, Confocal
- Molecular Sequence Data
- Mutation
- Peptide Fragments
- Triterpenes