Article
A global test for groups of genes: testing association with a clinical outcome.
Bioinformatics (Oxford, England) - 1 Jan 2004
Goeman Jelle J, van de Geer Sara A, de Kort Floor, van Houwelingen Hans C
Abstract excerpt
MOTIVATION: This paper presents a global test to be used for the analysis of microarray data. Using this test it can be determined whether the global expression pattern of a group of genes is significantly related to some clinical outcome of interest. Groups of genes may be any size from a single gene to all genes on the chip (e.g. known pathways, specific areas of the genome or clusters from a cluster analysis)....
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