Article
Sequencing of Neisseria meningitidis penA gene: the key to success in defining penicillin G breakpoints.
Antimicrobial agents and chemotherapy - 1 Jan 2004
Arreaza Luisa, Salcedo Celia, Alcalá Belén, Uría María José, Abad Raquel, Enríquez Rocío, Vázquez Julio A
Abstract excerpt
Testing of susceptibility to penicillin G by E-test and sequencing of an internal fragment of the penA gene were done for 43 meningococcal strains. Those strains for which the MIC was >/=0.094 micro g/ml showed mosaic alleles, so 0.094 micro g/ml is suggested as the penicillin G intermediate breakpoint when E-test is used.
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