Article
Pseudomembranous colitis caused by toxin A-negative/toxin B-positive variant strain of Clostridium difficile.
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy - 1 Dec 2003
Toyokawa Masahiro, Ueda Akiko, Tsukamoto Hisako, Nishi Isao, Horikawa Masayuki, Sunada Atsuko, Asari Seishi
Abstract excerpt
We report the first case of pseudomembranous colitis (PMC) due to a toxin A-negative, toxin B-positive strain (toxin A variant strain) of Clostridium difficile in Japan. The toxin A variant strain of C. difficile is capable of causing PMC and is undetectable in clinical laboratories that use only toxin A immunoassays for C. difficile testing. If C. difficile-associated diarrhea is clinically suspected and toxin A...
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