Effects of lifestyle intervention on weight and metabolic parameters in patients with impaired glucose tolerance related to beta-3 adrenergic receptor gene polymorphism Trp64Arg(C/T): Results from the Japan Diabetes Prevention Program.

doi:10.1111/jdi.12426

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Article

Effects of lifestyle intervention on weight and metabolic parameters in patients with impaired glucose tolerance related to beta-3 adrenergic receptor gene polymorphism Trp64Arg(C/T): Results from the Japan Diabetes Prevention Program.

Journal of diabetes investigation - 1 May 2016

Sakane Naoki, Sato Juichi, Tsushita Kazuyo, Tsujii Satoru, Kotani Kazuhiko, Tominaga Makoto, Kawazu Shoji, Sato Yuzo, Usui Takeshi, Kamae Isao, Yoshida Toshihide, Kiyohara Yutaka, Sato Shigeaki, Tsuzaki Kokoro, Takahashi Kaoru, Kuzuya Hideshi

Abstract excerpt

The beta-3 adrenergic receptor (ADRB3), primarily expressed in adipose tissue, is involved in the regulation of energy metabolism. The present study hypothesized that ADRB3 (Trp64Arg, rs4994) polymorphisms modulate the effects of lifestyle intervention on weight and metabolic parameters in patients with impaired glucose tolerance. Data were analyzed from 112 patients with impaired glucose tolerance in the Japan...

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Identifiers

PMID: 27330719
DOI: 10.1111/jdi.12426
PMCID: PMC4847887

Genes

ADRB3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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Effects of lifestyle intervention on weight and metabolic parameters in patients with impaired glucose tolerance related to beta-3 adrenergic receptor gene polymorphism Trp64Arg(C/T): Results from the Japan Diabetes Prevention Program.PMID 27330719Read ↗

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