Article
A strategy to improve the efficacy of vaccination against tuberculosis and leprosy.
Immunology today - 1 Sept 1992
Bretscher P A
Abstract excerpt
The pathogens responsible for leprosy, tuberculosis and the leishmaniases can induce different classes of immunity, but protection is provided only by a cell-mediated response. Here, Peter Bretscher proposes a strategy to achieve an immunological imprint that ensures a stable cell-mediated respon...
Topics
- Animals
- BCG Vaccine
- Bacterial Vaccines
- Disease Susceptibility
- Dose-Response Relationship, Immunologic
- Genetic Predisposition to Disease
- Humans
- Hypersensitivity, Delayed
- Immunity, Cellular
- Immunity, Innate
- Leishmania tropica
- Leishmaniasis, Cutaneous
- Leprosy
- Mice
- Mice, Inbred BALB C
- Mycobacterium bovis
- Mycobacterium leprae
- Mycobacterium tuberculosis