Article
New quantitative trait loci for the genetic variance in circadian period of locomotor activity between inbred strains of mice.
Journal of biological rhythms - 1 Dec 2003
Hofstetter J R, Trofatter J A, Kernek K L, Nurnberger J I, Mayeda A R
Abstract excerpt
Provisional quantitative trait loci (QTL) for circadian locomotor period and wheel-running period have been identified in recombinant inbred (RI) mouse strains. To confirm those QTL and identify new ones, the genetic component of variance of the circadian period was partitioned among an F2 intercross of RI mouse strains (BXD19 and CXB07). First, a genomic survey using 108 SSLP markers with an average spacing of...
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