Article
A distinct phenotype characterizes tumors from a putative genetic trait involving chondrosarcoma and breast cancer occurring in the same patient.
Laboratory investigation; a journal of technical methods and pathology - 1 Feb 2004
Cleton-Jansen Anne-Marie, Timmerman Michel C, van de Vijver Marc J, van Asperen Christi J, Kroon Herman M, Eilers Paul H C, Hogendoorn Pancras C W
Abstract excerpt
Recently, we documented an increased risk for the occurrence of breast- and cartilaginous tumors in the same patient, statistically pointing towards a potential genetic trait. This trait is most probably not associated with mutations in the two major hereditary breast cancer genes since no cases of enchondroma or chondrosarcoma were found in Dutch BRCA1 and BRCA2 families. We were able to collect and review the...
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